RadMaps: A Geospatial Framework for Simultaneously Modelling Capacity and Geographic Constraints on Radiotherapy Access
Pith reviewed 2026-05-25 02:33 UTC · model grok-4.3
The pith
RadMaps reveals that capacity and geographic constraints together limit global radiotherapy access to 60%.
A machine-rendered reading of the paper's core claim, the machinery that carries it, and where it could break.
Core claim
The RadMaps framework, when applied globally with a 200 km step-function access threshold, computes a capacity-only access of 70%, a geography-only access of 91%, and a combined RT access of 60%, showing the compounding effect of the two constraints.
What carries the argument
A greedy nearest-first allocation algorithm that assigns demand to facilities subject to both capacity and geographic constraints, producing a localised access metric for every H3 hexagon.
If this is right
- The tool can localise access deficits at sub-national scale in individual countries.
- It identifies distinct access profiles including capacity-limited, geographically-limited, and doubly-constrained regions.
- The modular framework supports infrastructure planning and policy prioritisation at regional to global scales.
Where Pith is reading between the lines
- The allocation method could be tested against real-world patient flow data to validate its accuracy.
- Extending the model to include public transport times might change access estimates in urban versus rural areas.
- Similar simultaneous constraint modeling could be applied to other healthcare services like chemotherapy or surgery.
Load-bearing premise
The greedy nearest-first allocation algorithm accurately assigns demand to facilities under simultaneous capacity and geographic constraints.
What would settle it
Direct measurement of actual radiotherapy utilization rates in a country compared against the model's predicted access percentages for its regions.
Figures
read the original abstract
Background: Access to radiotherapy (RT) is constrained by two compounding factors: insufficient machine capacity to meet patient demand and geographic distance from treatment facilities. Existing analyses address these factors separately, constraining the insights available to planners and policymakers. This paper presents RadMaps, an open-source geospatial framework that simultaneously models capacity and geographic constraints on RT access at any spatial scale. Methods: RadMaps operates on Uber's H3 hexagonal grid and integrates population density data with national cancer incidence estimates and RT facility inventories. RT demand is estimated using cancer-site-specific RT utilisation rates, and geographic access is modelled via configurable decay functions using either distance, driving time, or public transport time. A greedy nearest-first allocation algorithm assigns demand to facilities subject to both capacity and geographic constraints, producing a localised access metric for every H3 hexagon. Results: Applied globally with a 200 km step-function access threshold, RadMaps computes a capacity-only access of 70 %, a geography-only access of 91 %, and a combined RT access of 60 %, illustrating the compounding effect of capacity and geographic constraints to significantly reduce effective access. High-resolution analyses of six countries demonstrate the tool's ability to localise access deficits at sub-national scale and reveal distinct access profiles: capacity-limited, geographically-limited, and doubly-constrained. Conclusions: RadMaps provides a flexible, open-access framework for visualising and identifying RT access gaps at regional to global scales, with applications in infrastructure planning and policy prioritisation. RadMaps' modular framework is also readily extensible to other spatial access modelling applications.
Editorial analysis
A structured set of objections, weighed in public.
Referee Report
Summary. The paper presents RadMaps, an open-source geospatial framework operating on Uber's H3 hexagonal grid that integrates population density, cancer incidence estimates, and RT facility inventories to simultaneously model capacity and geographic constraints on radiotherapy access. Demand is estimated via site-specific utilisation rates and assigned via a greedy nearest-first algorithm subject to configurable decay functions (distance or time); global application with a 200 km step-function threshold yields capacity-only access of 70%, geography-only access of 91%, and combined access of 60%, with sub-national profiles shown for six countries.
Significance. If externally validated, the framework's modular, open-source design would be a useful contribution for visualising and prioritising RT access gaps at multiple scales. The explicit separation of capacity-only, geography-only, and joint metrics, together with the provision of reproducible code, strengthens the potential utility for infrastructure planning.
major comments (2)
- [Results] Results section: the central global figures (70 % capacity-only, 91 % geography-only, 60 % combined) are presented as direct evidence of compounding constraints without reported sensitivity analyses on the 200 km threshold, utilisation rates, or decay functions, and without comparison to independent national RT utilisation or travel-distance statistics; this absence is load-bearing for the claim that the model illustrates a significant reduction in effective access.
- [Methods] Methods section: the greedy nearest-first allocation algorithm is invoked to generate the localised access metric for every H3 hexagon under simultaneous constraints, yet no robustness checks against alternative assignment rules (e.g., capacity-proportional or optimisation-based) are provided, leaving the quantitative outputs dependent on an untested modeling choice.
minor comments (1)
- [Abstract] Abstract: the description of 'configurable decay functions' does not indicate which function (step-function at 200 km) was used for the global results, reducing clarity for readers.
Simulated Author's Rebuttal
We thank the referee for their thoughtful review and constructive feedback. We agree that additional robustness checks will strengthen the manuscript and address concerns about the sensitivity of the reported global access estimates. Below we respond point-by-point to the major comments.
read point-by-point responses
-
Referee: [Results] Results section: the central global figures (70 % capacity-only, 91 % geography-only, 60 % combined) are presented as direct evidence of compounding constraints without reported sensitivity analyses on the 200 km threshold, utilisation rates, or decay functions, and without comparison to independent national RT utilisation or travel-distance statistics; this absence is load-bearing for the claim that the model illustrates a significant reduction in effective access.
Authors: We agree that the absence of sensitivity analyses and external comparisons limits the strength of the claim regarding compounding constraints. In the revised manuscript we will add a dedicated sensitivity analysis subsection in Results, testing the 200 km threshold at 100 km, 150 km and 250 km, varying utilisation rates within published ranges for each cancer site, and comparing step-function versus linear and exponential decay. Where independent national RT utilisation or travel-time statistics exist in the literature, we will add direct comparisons and report agreement or discrepancies. These additions will be presented alongside the original global figures. revision: yes
-
Referee: [Methods] Methods section: the greedy nearest-first allocation algorithm is invoked to generate the localised access metric for every H3 hexagon under simultaneous constraints, yet no robustness checks against alternative assignment rules (e.g., capacity-proportional or optimisation-based) are provided, leaving the quantitative outputs dependent on an untested modeling choice.
Authors: The greedy nearest-first rule was chosen for computational tractability at global scale and because it approximates observed patient behaviour of selecting the closest facility with available capacity. We acknowledge that alternative rules could affect quantitative outputs. In the revision we will add a supplementary analysis applying a capacity-proportional allocation rule to the six profiled countries and report the resulting changes in combined access percentages. This will allow readers to assess the sensitivity of the headline metrics to the allocation choice and will be discussed in the Methods and Results sections. revision: yes
Circularity Check
No circularity; model outputs computed from external inputs via explicit algorithm
full rationale
The paper presents RadMaps as a geospatial simulation that ingests external population, incidence, and facility inventories, applies configurable decay functions and a greedy nearest-first allocation procedure, and emits access percentages as direct model outputs. No equations, fitted parameters, or self-citations are shown that would make the reported 70/91/60 % figures equivalent to the inputs by construction. The derivation chain is self-contained against the stated data sources and algorithmic choices; the central claims are simulation results rather than tautological reductions.
Axiom & Free-Parameter Ledger
free parameters (2)
- access threshold =
200 km
- decay functions
axioms (2)
- domain assumption National cancer incidence estimates and site-specific RT utilisation rates accurately reflect local demand
- domain assumption Greedy nearest-first allocation produces a realistic assignment of patients to facilities
Reference graph
Works this paper leans on
-
[1]
Delaney, Geoff and Jacob, Susannah and Featherstone, Carolyn and Barton, Michael , title =. Cancer , volume =. doi:https://doi.org/10.1002/cncr.21324 , url =. https://acsjournals.onlinelibrary.wiley.com/doi/pdf/10.1002/cncr.21324 , year =
-
[2]
Barton and Susannah Jacob and Jesmin Shafiq and Karen Wong and Stephen R
Michael B. Barton and Susannah Jacob and Jesmin Shafiq and Karen Wong and Stephen R. Thompson and Timothy P. Hanna and Geoff P. Delaney , keywords =. Estimating the demand for radiotherapy from the evidence: A review of changes from 2003 to 2012 , journal =. 2014 , issn =. doi:https://doi.org/10.1016/j.radonc.2014.03.024 , url =
-
[3]
Brown, Katrina F. and Rumgay, Harriet and Dunlop, Catherine and Ryan, Michael and Quartly, Robert and Cox, Amanda and Deas, Anne and Lyon, Ruth and Beattie, Lynn and Oliphant, Rowena and Ormiston-Rees, Rebecca and Samuel, Gini and White, Claire and Parkin, Donald Max , title =. British Journal of Cancer , year =. doi:10.1038/s41416-018-0029-6 , url =
-
[4]
World Cancer Report: Cancer Research for Cancer Prevention , editor =. 2020 , publisher =
work page 2020
-
[5]
Journal of Global Oncology , volume =
Yap, Mei Ling and Zubizarreta, Eduardo and Bray, Freddie and Ferlay, Jacques and Barton, Michael , title =. Journal of Global Oncology , volume =. 2016 , doi =
work page 2016
-
[6]
Fabio Y. Moraes and Andre G. Gouveia and Vanessa Freitas Bratti and Edward C. Dee and Juliana Fernandes Pavoni and Laura M. Carson and Cecília Félix Penido Mendes de Sousa and Richard Sullivan and Gustavo Nader Marta and Wilma M. Hopman and Christopher M. Booth and Ajay Aggarwal and Ahmedin Jemal and Timothy P. Hanna and Brooke E. Wilson and Gustavo Arrud...
-
[7]
E. H. Zubizarreta and E. Fidarova and B. Healy and E. Rosenblatt , doi =. Need for Radiotherapy in Low and Middle Income Countries – The Silent Crisis Continues , volume =. Clinical Oncology , keywords =
-
[8]
Dominik Wawrzuta and Justyna Klejdysz and Katarzyna Pędziwiatr and Marzanna Chojnacka , doi =. Global access to radiotherapy: A geospatial analysis of current disparities and optimal facility placement , volume =. Radiotherapy and Oncology , keywords =
-
[9]
Silverwood and Kathleen Waeldner and Sasha K
Sierra M. Silverwood and Kathleen Waeldner and Sasha K. Demeulenaere and Shavit Keren and Jason To and Jie Jane Chen and Zakaria El Kouzi and Alan Ayoub and Surbhi Grover and Katie E. Lichter and Osama Mohamad , doi =. The Relationship Between Travel Distance for Treatment and Outcomes in Patients Undergoing Radiation Therapy: A Systematic Review , volume...
-
[10]
GitHub repository , howpublished =
Uber , title =. GitHub repository , howpublished =. 2025 , publisher =
work page 2025
-
[11]
Kontur Population Dataset , year =
-
[12]
and Soerjomataram, Isabelle and Jemal, Ahmedin , title =
Bray, Freddie and Laversanne, Mathieu and Sung, Hyuna and Ferlay, Jacques and Siegel, Rebecca L. and Soerjomataram, Isabelle and Jemal, Ahmedin , title =. CA: A Cancer Journal for Clinicians , volume =. doi:https://doi.org/10.3322/caac.21834 , url =. https://acsjournals.onlinelibrary.wiley.com/doi/pdf/10.3322/caac.21834 , year =
-
[13]
The IAEA Directory of Radiotherapy Centres (DIRAC) , howpublished =
-
[14]
and Soerjomataram, Isabelle and Bray, Freddie , title =
Fidler, Miranda M. and Soerjomataram, Isabelle and Bray, Freddie , title =. International Journal of Cancer , volume =. doi:https://doi.org/10.1002/ijc.30382 , url =. https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.30382 , year =
-
[15]
and Vaccarella, Salvatore and Bray, Freddie , title =
Fidler, Miranda M. and Vaccarella, Salvatore and Bray, Freddie , title =. Reducing social inequalities in cancer: evidence and priorities for research , editor =. 2019 , series =
work page 2019
-
[16]
Joel E. Segel and Eugene J. Lengerich , doi =. Rural-urban differences in the association between individual, facility, and clinical characteristics and travel time for cancer treatment , volume =. BMC Public Health 2020 20:1 , keywords =
work page 2020
-
[17]
Medical Journal of Australia , volume =
Baade, Peter D and Dasgupta, Paramita and Aitken, Joanne F and Turrell, Gavin , title =. Medical Journal of Australia , volume =. doi:https://doi.org/10.5694/mja10.11204 , url =. https://onlinelibrary.wiley.com/doi/pdf/10.5694/mja10.11204 , year =
-
[18]
Haffty and Kitaw Demissie , doi =
Sharad Goyal and Sheenu Chandwani and Bruce G. Haffty and Kitaw Demissie , doi =. Effect of Travel Distance and Time to Radiotherapy on Likelihood of Receiving Mastectomy , volume =. Annals of Surgical Oncology 2014 22:4 , keywords =
work page 2014
-
[19]
B.J. Healy and D. Cobalt-60 Machines and Medical Linear Accelerators: Competing Technologies for External Beam Radiotherapy , journal =. 2017 , note =. doi:https://doi.org/10.1016/j.clon.2016.11.002 , url =
-
[20]
Rifat Atun and David A. Jaffray and Michael B. Barton and Freddie Bray and Michael Baumann and Bhadrasain Vikram and Timothy P. Hanna and Felicia M. Knaul and Yolande Lievens and Tracey Y.M. Lui and Michael Milosevic and Brian O'Sullivan and Danielle L. Rodin and Eduardo Rosenblatt and Jacob Van Dyk and Mei Ling Yap and Eduardo Zubizarreta and Mary Gospod...
-
[21]
Peter Dunscombe and Cai Grau and Noémie Defourny and Julian Malicki and Josep M. Borras and Mary Coffey and Marta Bogusz and Chiara Gasparotto and Ben Slotman and Yolande Lievens and Arianit Kokobobo and Felix Sedlmayer and Elena Slobina and Olivier. Guidelines for equipment and staffing of radiotherapy facilities in the European countries: Final results ...
-
[22]
GitHub repository , howpublished =
CARTO Basemap Styles License , year =. GitHub repository , howpublished =
-
[23]
Melanie Turner and Romi Carriere and Shona Fielding and George Ramsay and Leslie Samuel and Andrew Maclaren and Peter Murchie , keywords =. The impact of travel time to cancer treatment centre on post-diagnosis care and mortality among cancer patients in Scotland , journal =. 2023 , issn =. doi:https://doi.org/10.1016/j.healthplace.2023.103139 , url =
-
[24]
Melanie Turner and Samuel Kent and Sharon Hanley and Peter Murchie , keywords =. Exploring associations between travel burden, clinical features, and outcomes from head and neck cancer in Scotland, UK , journal =. 2026 , issn =. doi:https://doi.org/10.1016/j.canep.2026.103012 , url =
discussion (0)
Sign in with ORCID, Apple, or X to comment. Anyone can read and Pith papers without signing in.