Birationality of the tangent map for minimal rational curves

For a uniruled projective manifold, we prove that a general rational curve of minimal degree through a general point is uniquely determined by its tangent vector. As applications, among other things we give a new proof, using no Lie theory, of our earlier result that a holomorphic map from a rational homogeneous space of Picard number 1 onto a projective manifold different from the projective space must be a biholomorphic map.