Pith Number

pith:3REU6LB2

pith:2026:3REU6LB2P6VKWK23IH3PXTI5HH

not attested not anchored not stored refs resolved

Kin-ematic Exclusion in Active Matter: Modelling Mutual Inhibition in \textit{Pseudomonas aeruginosa} Sibling Colonies

Barbara Capone, Dario Buonomo, Fabio Bruni, Francesco Imperi, Marco Polin

Sibling colonies of Pseudomonas aeruginosa separate because local nutrient depletion slows growth and motility in a self-reinforcing way.

arxiv:2605.13927 v1 · 2026-05-13 · q-bio.CB · physics.bio-ph

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\usepackage{pith}
\pithnumber{3REU6LB2P6VKWK23IH3PXTI5HH}

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Record completeness

1 Bitcoin timestamp

2 Internet Archive

3 Author claim open · sign in to claim

4 Citations open

5 Replications open

✓ Portable graph bundle live · download bundle · merged state

The bundle contains the canonical record plus signed events. A mirror can host it anywhere and recompute the same current state with the deterministic merge algorithm.

Claims

C1strongest claim

colony separation is driven by localised nutrient depletion through a dynamic feedback between growth and motility

C2weakest assumption

The experiments have fully ruled out gel compression, lethal inhibition and quorum sensing as contributors, so the nutrient-motility mechanism is the dominant cause.

C3one line summary

Sibling inhibition between isogenic P. aeruginosa colonies arises from nutrient depletion feedback on growth and motility rather than gel compression, lethality, or quorum sensing.

References

60 extracted · 60 resolved · 0 Pith anchors

[1] Y. M. Bar-On, R. Phillips, and R. Milo, Proceedings of the National Academy of Sciences115, 6506 (2018) 2018

[2] F. Azam and F. Malfatti, Nature reviews. Microbiology 5, 782 (2007) 2007

[3] Stocker, Science338, 628 (2012) 2012

[4] T. Bhattacharjee, D. B. Amchin, J. A. Ott, F. Kratz, and S. S. Datta, Biophysical Journal120, 3483 (2021) 2021

[5] A. Wolfe and H. Berg, Proceedings of the National Academy of Sciences of the United States of America 86, 6973 (1989) 1989

Receipt and verification

First computed	2026-05-17T23:39:14.020554Z
Builder	pith-number-builder-2026-05-17-v1
Signature	Pith Ed25519 (`pith-v1-2026-05`) · public key
Schema	pith-number/v1.0

Canonical hash

dc494f2c3a7faaab2b5b41f6fbcd1d39e9525b9219e3e475f15af543e308a266

Aliases

arxiv: 2605.13927 · arxiv_version: 2605.13927v1 · doi: 10.48550/arxiv.2605.13927 · pith_short_12: 3REU6LB2P6VK · pith_short_16: 3REU6LB2P6VKWK23 · pith_short_8: 3REU6LB2

Agent API

Resolver JSON Graph JSON Events JSON Schema Signing key

Verify this Pith Number yourself

curl -sH 'Accept: application/ld+json' https://pith.science/pith/3REU6LB2P6VKWK23IH3PXTI5HH \
  | jq -c '.canonical_record' \
  | python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: dc494f2c3a7faaab2b5b41f6fbcd1d39e9525b9219e3e475f15af543e308a266

Canonical record JSON

{
  "metadata": {
    "abstract_canon_sha256": "fa45343045c62ec56a74cfc5f5752d6bfbdbac5c8e0336b6072946a3279af4e5",
    "cross_cats_sorted": [
      "physics.bio-ph"
    ],
    "license": "http://creativecommons.org/licenses/by/4.0/",
    "primary_cat": "q-bio.CB",
    "submitted_at": "2026-05-13T15:43:56Z",
    "title_canon_sha256": "df69ad83a39449126513bd9572bccd34f11be55cbe6ba5b291607b13f0f40780"
  },
  "schema_version": "1.0",
  "source": {
    "id": "2605.13927",
    "kind": "arxiv",
    "version": 1
  }
}