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pith:7FWJ2TCP

pith:2026:7FWJ2TCPUTMWNZ24JFZHHWNCJU
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Rethinking Cross-Dose PET Denoising: Mitigating Averaging Effects via Residual Noise Learning

Junwen Guo, Yichao Liu, YueYang Teng, Zongru Shao

Estimating noise directly from low-dose PET images avoids the averaging effect in cross-dose denoising models.

arxiv:2604.16925 v3 · 2026-04-18 · cs.CV

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\pithnumber{7FWJ2TCPUTMWNZ24JFZHHWNCJU}

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3 Author claim open · sign in to claim
4 Citations open
5 Replications open
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Claims

C1strongest claim

We propose a unified residual noise learning framework that estimates noise directly from low-dose PET images rather than predicting full-dose images. Experiments on large-scale multi-dose PET datasets from two medical centers demonstrate that the proposed method outperforms the one-size-for-all model, individual dose-specific U-Net models, and dose-conditioned approaches.

C2weakest assumption

The central claim rests on the premise that the noise component in low-dose PET can be treated as an additive residual whose statistical properties are sufficiently independent of the underlying anatomy that a network can learn to predict it directly from the noisy input alone (abstract, paragraph on residual noise learning framework).

C3one line summary

The work introduces a residual noise learning framework for cross-dose PET denoising that avoids averaged mappings by estimating noise directly from low-dose inputs and shows gains over one-size-for-all and dose-specific baselines on multi-center data.

References

32 extracted · 32 resolved · 0 Pith anchors

[1] Positron-emission tomography and assessment of cancer therapy 2006
[2] A systematic review of pet and pet/ct in oncology: A way to personalize cancer treatment in a cost-effective manner? 2010
[3] The role of radiology in head and neck tumours in children, 2010
[4] Present and future roles of fdg-pet/ct imaging in the management of gastrointestinal cancer: an update, 2017
[5] Nsclc biomarkers to predict response to immunotherapy with checkpoint inhibitors (ici): From the cells to in vivo images, 2021

Formal links

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Receipt and verification
First computed 2026-05-20T00:00:38.356476Z
Builder pith-number-builder-2026-05-17-v1
Signature Pith Ed25519 (pith-v1-2026-05) · public key
Schema pith-number/v1.0

Canonical hash

f96c9d4c4fa4d966e75c497273d9a24d00fd58b00b57a9c1e414b7145d321a5b

Aliases

arxiv: 2604.16925 · arxiv_version: 2604.16925v3 · doi: 10.48550/arxiv.2604.16925 · pith_short_12: 7FWJ2TCPUTMW · pith_short_16: 7FWJ2TCPUTMWNZ24 · pith_short_8: 7FWJ2TCP
Agent API
Verify this Pith Number yourself
curl -sH 'Accept: application/ld+json' https://pith.science/pith/7FWJ2TCPUTMWNZ24JFZHHWNCJU \
  | jq -c '.canonical_record' \
  | python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: f96c9d4c4fa4d966e75c497273d9a24d00fd58b00b57a9c1e414b7145d321a5b
Canonical record JSON
{
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    "cross_cats_sorted": [],
    "license": "http://creativecommons.org/licenses/by/4.0/",
    "primary_cat": "cs.CV",
    "submitted_at": "2026-04-18T09:16:38Z",
    "title_canon_sha256": "ce8097f7837d50cc8b7b9793d2eb98235b073a1d8a239b1ed91184ec26667444"
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  "source": {
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    "kind": "arxiv",
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}