pith:A5P2CBIQ
Adsorption of mono- and multivalent cat- and anions on DNA molecules
DNA geometry dictates where salt ions adsorb: cylindrical models favor phosphate strands while grooved models favor the minor groove.
arxiv:cond-mat/0307079 v1 · 2003-07-03 · cond-mat.soft · cond-mat.stat-mech · q-bio
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Claims
The adsorption pattern on the DNA surface depends strongly on its geometrical shape: counterions adsorb preferentially along the phosphate strands for a cylindrical model shape, but in the minor groove for a geometrically structured model.
The hard-sphere ion model and the chosen point-charge placement on the phosphate strands are sufficient to capture the dominant electrostatic and steric effects that determine adsorption sites in real hydrated DNA.
Simulations reveal that DNA geometry dictates ion adsorption sites, with minor-groove preference for structured models, salt-independent major-groove neutralization, and overcharging by multivalent ions.
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Receipt and verification
| First computed | 2026-07-04T16:39:07.758588Z |
|---|---|
| Builder | pith-number-builder-2026-05-17-v1 |
| Signature | Pith Ed25519
(pith-v1-2026-05) · public key |
| Schema | pith-number/v1.0 |
Canonical hash
075fa10510e1c4319afa112c8c208a28ccf12f4ce25a81077d174ae557e6ac76
Aliases
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Verify this Pith Number yourself
curl -sH 'Accept: application/ld+json' https://pith.science/pith/A5P2CBIQ4HCDDGX2CEWIYIEKFD \
| jq -c '.canonical_record' \
| python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: 075fa10510e1c4319afa112c8c208a28ccf12f4ce25a81077d174ae557e6ac76
Canonical record JSON
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"submitted_at": "2003-07-03T14:42:55Z",
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