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Pith Number

pith:GAPQ5F2G

pith:2026:GAPQ5F2GWCCQCQT2BD75JWKNGD
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Letting the neural code speak: Automated characterization of monkey visual neurons through human language

Andreas S. Tolias, Katrin Franke, Nikos Karantzas, Sophia Sanborn, Surya Ganguli, Tamar Rott Shaham, Vedang Lad

Natural language descriptions capture the selectivity of most neurons in macaque V1 and V4.

arxiv:2605.12485 v2 · 2026-05-12 · q-bio.NC · q-bio.QM

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\pithnumber{GAPQ5F2GWCCQCQT2BD75JWKNGD}

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4 Citations open
5 Replications open
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The bundle contains the canonical record plus signed events. A mirror can host it anywhere and recompute the same current state with the deterministic merge algorithm.

Claims

C1strongest claim

Across macaque V1 and V4, the selectivity of most neurons is captured by concise, verifiable semantic descriptions; in V4, images generated from activating and suppressing hypotheses drove 96.1% of neurons above the 95th and 97.6% below the 5th percentile of natural-image responses, respectively.

C2weakest assumption

That the digital-twin models of V1 and V4 faithfully reproduce the response statistics of real biological neurons for the novel synthetic images generated from language hypotheses.

C3one line summary

Natural-language descriptions generated and verified through generative models and digital twins capture the selectivity of most neurons in macaque V1 and V4.

Receipt and verification
First computed 2026-05-20T00:04:36.600846Z
Builder pith-number-builder-2026-05-17-v1
Signature Pith Ed25519 (pith-v1-2026-05) · public key
Schema pith-number/v1.0

Canonical hash

301f0e9746b08501427a08ffd4d94d30fdb07625a82e13dbc57e73f0402eaa3b

Aliases

arxiv: 2605.12485 · arxiv_version: 2605.12485v2 · doi: 10.48550/arxiv.2605.12485 · pith_short_12: GAPQ5F2GWCCQ · pith_short_16: GAPQ5F2GWCCQCQT2 · pith_short_8: GAPQ5F2G
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Verify this Pith Number yourself
curl -sH 'Accept: application/ld+json' https://pith.science/pith/GAPQ5F2GWCCQCQT2BD75JWKNGD \
  | jq -c '.canonical_record' \
  | python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: 301f0e9746b08501427a08ffd4d94d30fdb07625a82e13dbc57e73f0402eaa3b
Canonical record JSON
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    "license": "http://creativecommons.org/licenses/by/4.0/",
    "primary_cat": "q-bio.NC",
    "submitted_at": "2026-05-12T17:58:22Z",
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