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RISED: A Pre-Deployment Safety Evaluation Framework for Clinical AI Decision-Support Systems

Rohith Reddy Bellibatlu

Clinical AI models that pass standard accuracy tests can fail on input stability and threshold sensitivity.

arxiv:2605.12895 v1 · 2026-05-13 · cs.LG · cs.AI · cs.CY · stat.AP

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Claims

C1strongest claim

A classifier satisfying conventional high-discrimination benchmarks can simultaneously fail input-encoding stability and threshold-shift sensitivity checks, while subgroup AUC parity remains statistically inconclusive, pointing to deployment risks that aggregate evaluation alone cannot detect.

C2weakest assumption

That the five chosen dimensions and their operationalized sub-criteria with pre-specified thresholds adequately capture the primary pre-deployment risks for clinical AI systems across diverse datasets and use cases.

C3one line summary

RISED is a structured pre-deployment safety framework that flags failures in clinical AI systems across reliability, inclusivity, sensitivity, equity, and deployability using pre-specified criteria and statistical corrections, even when aggregate accuracy looks strong.

References

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[1] and Torkamani, Ali and Dias, Raquel and Gianfrancesco, Milena and Arnaout, Rima and Kohane, Isaac S
[2] and Porras, Antonio R
[3] and Calvert, Melanie J
[4] and Denniston, Alastair K
[5] Journal of the American Statistical Association , year =
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First computed 2026-05-18T03:09:10.861765Z
Builder pith-number-builder-2026-05-17-v1
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431a9a247a19f70d787cb81ff71b58aea165c38cb2824b9df4913ffc631cf61e

Aliases

arxiv: 2605.12895 · arxiv_version: 2605.12895v1 · doi: 10.48550/arxiv.2605.12895 · pith_short_12: IMNJUJD2DH3Q · pith_short_16: IMNJUJD2DH3Q26D4 · pith_short_8: IMNJUJD2
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curl -sH 'Accept: application/ld+json' https://pith.science/pith/IMNJUJD2DH3Q26D4XAP7OG2YV2 \
  | jq -c '.canonical_record' \
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Canonical record JSON
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