Pith Number

pith:JANLBFF7

pith:2020:JANLBFF7BAVHETOA4GRX2JGEQP

not attested not anchored not stored refs pending

What Were They Thinking? Pharmacologic priors implicit in a choice of 3+3 dose-escalation design

David C. Norris

arxiv:2012.05301 v2 · 2020-12-09 · stat.ME · q-bio.QM · stat.AP

Open paper page JSON Open Graph Bundle Merged state Verified badge What is a Pith Number?

Add to your LaTeX paper

\usepackage{pith}
\pithnumber{JANLBFF7BAVHETOA4GRX2JGEQP}

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Record completeness

1 Bitcoin timestamp

2 Internet Archive

3 Author claim open · sign in to claim

4 Citations open

5 Replications open

✓ Portable graph bundle live · download bundle · merged state

The bundle contains the canonical record plus signed events. A mirror can host it anywhere and recompute the same current state with the deterministic merge algorithm.

Cited by

1 paper in Pith

Dose-Escalation Trial Protocols that Extend Naturally to Admit Titration

Receipt and verification

First computed	2026-07-05T02:01:55.434381Z
Builder	pith-number-builder-2026-05-17-v1
Signature	Pith Ed25519 (`pith-v1-2026-05`) · public key
Schema	pith-number/v1.0

Canonical hash

481ab094bf082a724dc0e1a37d24c483ce4ed0d5d51d79c6959deef0d979f620

Aliases

arxiv: 2012.05301 · arxiv_version: 2012.05301v2 · doi: 10.48550/arxiv.2012.05301 · pith_short_12: JANLBFF7BAVH · pith_short_16: JANLBFF7BAVHETOA · pith_short_8: JANLBFF7

Agent API

Resolver JSON Graph JSON Events JSON Schema Signing key

Verify this Pith Number yourself

curl -sH 'Accept: application/ld+json' https://pith.science/pith/JANLBFF7BAVHETOA4GRX2JGEQP \
  | jq -c '.canonical_record' \
  | python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: 481ab094bf082a724dc0e1a37d24c483ce4ed0d5d51d79c6959deef0d979f620

Canonical record JSON

{
  "metadata": {
    "abstract_canon_sha256": "9711e9783f2c75b446d10e08795b5882396ecf2b9a953282ce9aa3ca09261224",
    "cross_cats_sorted": [
      "q-bio.QM",
      "stat.AP"
    ],
    "license": "http://creativecommons.org/licenses/by/4.0/",
    "primary_cat": "stat.ME",
    "submitted_at": "2020-12-09T20:33:38Z",
    "title_canon_sha256": "79204dab53ce11f4074d42d46485fd8cb9d738b041da95b9e7177354b9a9db77"
  },
  "schema_version": "1.0",
  "source": {
    "id": "2012.05301",
    "kind": "arxiv",
    "version": 2
  }
}