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pith:2026:MBW4CJ3V2OKVXNOQMDQVO5U4OK
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Uncertainty-Aware Image Classification In Biomedical Imaging Using Spectral-normalized Neural Gaussian Processes

Jeffrey J. Nirschl, Uma Meleti

Spectral-normalized neural Gaussian processes deliver accurate biomedical image classification with improved uncertainty estimates for out-of-distribution inputs.

arxiv:2602.02370 v2 · 2026-02-02 · cs.CV

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Claims

C1strongest claim

SNGP has comparable in-distribution performance while significantly improving uncertainty estimation and OOD detection.

C2weakest assumption

The chosen OOD test sets accurately represent the distribution shifts that occur in real clinical pathology workflows.

C3one line summary

SNGP models match deterministic neural network accuracy on biomedical images while providing superior uncertainty calibration and OOD rejection across six datasets.

References

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[1] Uncertainty-Aware Image Classification In Biomedical Imaging Using Spectral-normalized Neural Gaussian Processes 2026 · arXiv:2602.02370
[2] Bayesian neural networks provide a formal approach to uncertainty estimation but are compu- tationally impractical for large architectures
[3] Datasets All datasets are publicly available from the original authors or MicroBench [10] 2020
[4] RESULTS Tab.1 summarizes the OOD detection performance of all methods trained on the Acevedo dataset. SNGP achieved near-perfect OOD-AUROC across all external OOD datasets (0.97–1.00), while maintaini
[5] Across multiple datasets, it maintains strong calibration and in- distribution accuracy while substantially improving OOD detection over deterministic and Monte Carlo methods

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First computed 2026-06-19T16:11:20.290882Z
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606dc12775d3955bb5d060e157769c72bddc10e800cc7a01d0cd460148f217dd

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arxiv: 2602.02370 · arxiv_version: 2602.02370v2 · doi: 10.48550/arxiv.2602.02370 · pith_short_12: MBW4CJ3V2OKV · pith_short_16: MBW4CJ3V2OKVXNOQ · pith_short_8: MBW4CJ3V
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