Pith Number

pith:QVGDYG7I

pith:2026:QVGDYG7ILBNFFIEDSHV6TIKYYZ

not attested not anchored not stored refs pending

Adaptive clinical trials based on design-optimal e-values with automatic curtailment: An application to single-arm trials with binary data

Joost van Rosmalen, Judith ter Schure, Stef Baas

arxiv:2605.28653 v1 · 2026-05-27 · stat.ME

Open paper page JSON Open Graph Bundle Merged state Verified badge What is a Pith Number?

Add to your LaTeX paper

\usepackage{pith}
\pithnumber{QVGDYG7ILBNFFIEDSHV6TIKYYZ}

Prints a linked badge after your title and injects PDF metadata. Compiles on arXiv. Learn more · Embed verified badge

Record completeness

1 Bitcoin timestamp

2 Internet Archive

3 Author claim open · sign in to claim

4 Citations open

5 Replications open

✓ Portable graph bundle live · download bundle · merged state

The bundle contains the canonical record plus signed events. A mirror can host it anywhere and recompute the same current state with the deterministic merge algorithm.

Receipt and verification

First computed	2026-05-28T02:04:58.958040Z
Builder	pith-number-builder-2026-05-17-v1
Signature	Pith Ed25519 (`pith-v1-2026-05`) · public key
Schema	pith-number/v1.0

Canonical hash

854c3c1be8585a52a08391ebe9a158c66f6e1d1c0e0ddc953f1ba95e2d643041

Aliases

arxiv: 2605.28653 · arxiv_version: 2605.28653v1 · doi: 10.48550/arxiv.2605.28653 · pith_short_12: QVGDYG7ILBNF · pith_short_16: QVGDYG7ILBNFFIED · pith_short_8: QVGDYG7I

Agent API

Resolver JSON Graph JSON Events JSON Schema Signing key

Verify this Pith Number yourself

curl -sH 'Accept: application/ld+json' https://pith.science/pith/QVGDYG7ILBNFFIEDSHV6TIKYYZ \
  | jq -c '.canonical_record' \
  | python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: 854c3c1be8585a52a08391ebe9a158c66f6e1d1c0e0ddc953f1ba95e2d643041

Canonical record JSON

{
  "metadata": {
    "abstract_canon_sha256": "49fbbff8d8b81b8000f6ff94a45717fc82f418bfa11d2b30a5a83364f404653c",
    "cross_cats_sorted": [],
    "license": "http://creativecommons.org/licenses/by/4.0/",
    "primary_cat": "stat.ME",
    "submitted_at": "2026-05-27T15:54:32Z",
    "title_canon_sha256": "8fa070bb1928d2c1582b11a6c5454d023c4cc16b7849bcfa9425d6302e4489f8"
  },
  "schema_version": "1.0",
  "source": {
    "id": "2605.28653",
    "kind": "arxiv",
    "version": 1
  }
}