Pith Number

pith:S22HGXHG

pith:2026:S22HGXHGQ3HVJ55QDHRZ7L5LF2

not attested not anchored not stored refs resolved

Actin cross-linking organizes basal body patterning through anomalous diffusion transitions

Jakub Sedzinski, Mandar M. Inamdar, Poul-Martin Bendix, Raghavan Thiagarajan, Younes Farhangi Barooji

Actin cross-linking shifts basal bodies from diffusive to confined motion, producing uniform patterning for aligned cilia.

arxiv:2605.15912 v1 · 2026-05-15 · cond-mat.soft · physics.bio-ph · q-bio.SC

Open paper page JSON Open Graph Bundle Merged state Verified badge What is a Pith Number?

Add to your LaTeX paper

\usepackage{pith}
\pithnumber{S22HGXHGQ3HVJ55QDHRZ7L5LF2}

Prints a linked badge after your title and injects PDF metadata. Compiles on arXiv. Learn more · Embed verified badge

Record completeness

1 Bitcoin timestamp

2 Internet Archive

3 Author claim open · sign in to claim

4 Citations open

5 Replications open

✓ Portable graph bundle live · download bundle · merged state

The bundle contains the canonical record plus signed events. A mirror can host it anywhere and recompute the same current state with the deterministic merge algorithm.

Claims

C1strongest claim

progressive apical actin cross-linking coordinates BB positioning and regulates their dynamic state, guiding the shift from diffusive to confined motion. This transition in dynamics enables the emergence of a uniform BB pattern, which in turn ensures the aligned deployment of motile cilia necessary for effective directional fluid flow.

C2weakest assumption

The assumption that the observed correlation between increasing actin cross-linking and the shift to confined basal body motion is causal and not driven by other concurrent changes in cell size, membrane tension, or additional cytoskeletal components during the same developmental window.

C3one line summary

Progressive actin cross-linking in the apical cortex drives a transition from anomalous diffusion to confined motion of basal bodies, enabling uniform patterning for coordinated cilia function.

References

14 extracted · 14 resolved · 0 Pith anchors

[1] Metzner, C., Raupach, C., Paranhos Zitterbart, D. & Fabry, B. Simple model of cytoskeletal fluctuations.Physical Review E—Statistical, Nonlinear, and Soft Matter Physics76, 021925 (2007) 2007

[2] Nature communications12, 6253 (2021) 2021

[3] Davies, R. B. & Harte, D. S. Tests for Hurst effect.Biometrika74, 95–101 (1987) 1987

[4] Wood, A. T. A. & Chan, G. Simulation of stationary Gaussian processes in[0,1]d. Journal of Computational and Graphical Statistics3, 409–432 (1994) 1994

[5] fbm: Fractional brownian motion.https://pypi.org/project/fbm/ (2019) 2019

Formal links

2 machine-checked theorem links

Receipt and verification

First computed	2026-05-20T00:01:44.964609Z
Builder	pith-number-builder-2026-05-17-v1
Signature	Pith Ed25519 (`pith-v1-2026-05`) · public key
Schema	pith-number/v1.0

Canonical hash

96b4735ce686cf54f7b019e39fafab2e96101168eb36eed178100d4f6b0ea938

Aliases

arxiv: 2605.15912 · arxiv_version: 2605.15912v1 · doi: 10.48550/arxiv.2605.15912 · pith_short_12: S22HGXHGQ3HV · pith_short_16: S22HGXHGQ3HVJ55Q · pith_short_8: S22HGXHG

Agent API

Resolver JSON Graph JSON Events JSON Schema Signing key

Verify this Pith Number yourself

curl -sH 'Accept: application/ld+json' https://pith.science/pith/S22HGXHGQ3HVJ55QDHRZ7L5LF2 \
  | jq -c '.canonical_record' \
  | python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: 96b4735ce686cf54f7b019e39fafab2e96101168eb36eed178100d4f6b0ea938

Canonical record JSON

{
  "metadata": {
    "abstract_canon_sha256": "96e403702c4916ab999d68141aa7ce5fd14c355e66806d9a0cc096e83b0f246e",
    "cross_cats_sorted": [
      "physics.bio-ph",
      "q-bio.SC"
    ],
    "license": "http://creativecommons.org/licenses/by/4.0/",
    "primary_cat": "cond-mat.soft",
    "submitted_at": "2026-05-15T12:50:34Z",
    "title_canon_sha256": "5f9131486b98de33733fbdb01f23566a39b583afad6f4f63f09094d22554cccc"
  },
  "schema_version": "1.0",
  "source": {
    "id": "2605.15912",
    "kind": "arxiv",
    "version": 1
  }
}