pith:YLCNGINI
Learning Preference-Based Objectives from Clinical Narratives for Dynamic Sepsis Treatment
Clinical narratives supply preference signals that train rewards yielding better recovery in sequential treatment policies.
arxiv:2604.10783 v2 · 2026-04-12 · cs.AI · cs.LG
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Claims
The learned reward aligns strongly with trajectory quality (Spearman rho = 0.63) and enables policies that are consistently associated with improved recovery-related outcomes, including increased organ support-free days and faster shock resolution, while maintaining comparable performance on mortality. These effects persist under external validation.
That LLM-derived trajectory quality scores and pairwise preferences from discharge summaries accurately and unbiasedly reflect true clinical trajectory quality, patient preferences, and treatment effectiveness without significant influence from narrative variability, LLM biases, or selection effects in the data.
CN-PR learns reward functions from LLM-derived preferences over clinical trajectories to improve RL policies for sequential treatment decisions, showing correlation with quality scores and better recovery outcomes.
Receipt and verification
| First computed | 2026-05-26T02:05:09.220173Z |
|---|---|
| Builder | pith-number-builder-2026-05-17-v1 |
| Signature | Pith Ed25519
(pith-v1-2026-05) · public key |
| Schema | pith-number/v1.0 |
Canonical hash
c2c4d321a805c0e51443ac9cc1976b0fa1ef2c09358c360a5099042273c755f3
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· · · · ·Agent API
Verify this Pith Number yourself
curl -sH 'Accept: application/ld+json' https://pith.science/pith/YLCNGINIAXAOKFCDVSOMDF3LB6 \
| jq -c '.canonical_record' \
| python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: c2c4d321a805c0e51443ac9cc1976b0fa1ef2c09358c360a5099042273c755f3
Canonical record JSON
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