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pith:YLCNGINI

pith:2026:YLCNGINIAXAOKFCDVSOMDF3LB6
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Learning Preference-Based Objectives from Clinical Narratives for Dynamic Sepsis Treatment

Arturo Yong Yao Neo, Daniel J. Tan, Jayne Hui Zhen Chan, Kai Wen Hwang, Kay Choong See, Mengling Feng

Clinical narratives supply preference signals that train rewards yielding better recovery in sequential treatment policies.

arxiv:2604.10783 v2 · 2026-04-12 · cs.AI · cs.LG

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\pithnumber{YLCNGINIAXAOKFCDVSOMDF3LB6}

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3 Author claim open · sign in to claim
4 Citations open
5 Replications open
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The bundle contains the canonical record plus signed events. A mirror can host it anywhere and recompute the same current state with the deterministic merge algorithm.

Claims

C1strongest claim

The learned reward aligns strongly with trajectory quality (Spearman rho = 0.63) and enables policies that are consistently associated with improved recovery-related outcomes, including increased organ support-free days and faster shock resolution, while maintaining comparable performance on mortality. These effects persist under external validation.

C2weakest assumption

That LLM-derived trajectory quality scores and pairwise preferences from discharge summaries accurately and unbiasedly reflect true clinical trajectory quality, patient preferences, and treatment effectiveness without significant influence from narrative variability, LLM biases, or selection effects in the data.

C3one line summary

CN-PR learns reward functions from LLM-derived preferences over clinical trajectories to improve RL policies for sequential treatment decisions, showing correlation with quality scores and better recovery outcomes.

Receipt and verification
First computed 2026-05-26T02:05:09.220173Z
Builder pith-number-builder-2026-05-17-v1
Signature Pith Ed25519 (pith-v1-2026-05) · public key
Schema pith-number/v1.0

Canonical hash

c2c4d321a805c0e51443ac9cc1976b0fa1ef2c09358c360a5099042273c755f3

Aliases

arxiv: 2604.10783 · arxiv_version: 2604.10783v2 · doi: 10.48550/arxiv.2604.10783 · pith_short_12: YLCNGINIAXAO · pith_short_16: YLCNGINIAXAOKFCD · pith_short_8: YLCNGINI
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Verify this Pith Number yourself
curl -sH 'Accept: application/ld+json' https://pith.science/pith/YLCNGINIAXAOKFCDVSOMDF3LB6 \
  | jq -c '.canonical_record' \
  | python3 -c "import sys,json,hashlib; b=json.dumps(json.loads(sys.stdin.read()), sort_keys=True, separators=(',',':'), ensure_ascii=False).encode(); print(hashlib.sha256(b).hexdigest())"
# expect: c2c4d321a805c0e51443ac9cc1976b0fa1ef2c09358c360a5099042273c755f3
Canonical record JSON
{
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    "abstract_canon_sha256": "000828a8122a2c5b0e0f458508872216a5f59f3907c99e9daa8457c173ecbd7b",
    "cross_cats_sorted": [
      "cs.LG"
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    "license": "http://creativecommons.org/licenses/by/4.0/",
    "primary_cat": "cs.AI",
    "submitted_at": "2026-04-12T19:18:02Z",
    "title_canon_sha256": "9783c1112bd70d73fbe1e612a52a75ce9b5e47e274b99ecd93bc73b9581ce887"
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    "kind": "arxiv",
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