Benchmark of BINN, GraphPath, and PATH on 2622 TCGA patients shows PATH best for targeted therapy, BINN for survival, none useful for radiation, with GraphPath at 0.92 AUROC on prostate targeted therapy.
The Cancer Genome Atlas Pan - Cancer analysis project
3 Pith papers cite this work. Polarity classification is still indexing.
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A new open pipeline and dataset enable training of a vision-language model for whole-slide pathology VQA that outperforms MedGemma on tissue identification, neoplasm detection, and differential diagnosis.
Systematic benchmarking shows existing transcriptomic predictors for immune checkpoint inhibitor response have limited cross-cohort generalisability and inconsistent biomarker signals.
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TRAPS: Therapeutic Response Analysis via Pathway-informed Stratification
Benchmark of BINN, GraphPath, and PATH on 2622 TCGA patients shows PATH best for targeted therapy, BINN for survival, none useful for radiation, with GraphPath at 0.92 AUROC on prostate targeted therapy.
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Transcriptomic Models for Immunotherapy Response Prediction Show Limited Cross-cohort Generalisability
Systematic benchmarking shows existing transcriptomic predictors for immune checkpoint inhibitor response have limited cross-cohort generalisability and inconsistent biomarker signals.