LipoAgent coordinates fine-tuned LLM agents with a toxicity-first conditional prediction to improve lipid design for safer mRNA delivery, reporting 32% relative gains and wet-lab confirmation of virtual rankings.
Yizhen Zheng, Huan Yee Koh, Maddie Yang, Li Li, Lau- ren T
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The paper reduces a broad set of prompt engineering techniques to six core approaches and applies them to life sciences use cases while addressing common LLM pitfalls.
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LipoAgent: Coordinating Fine-Tuned LLM Agents for Safer Lipid Design
LipoAgent coordinates fine-tuned LLM agents with a toxicity-first conditional prediction to improve lipid design for safer mRNA delivery, reporting 32% relative gains and wet-lab confirmation of virtual rankings.