DPLM-Evo introduces an evolutionary discrete diffusion framework with explicit edit prediction and contextual noising that claims SOTA single-sequence mutation effect prediction on ProteinGym while supporting variable-length evolution simulation.
Fully non-autoregressive neural machine translation: Tricks of the trade
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Towards A Generative Protein Evolution Machine with DPLM-Evo
DPLM-Evo introduces an evolutionary discrete diffusion framework with explicit edit prediction and contextual noising that claims SOTA single-sequence mutation effect prediction on ProteinGym while supporting variable-length evolution simulation.