CAN-FLOW, a two-step conditional normalizing flow generator trained on LDDMM momenta from 2,208 UK Biobank hearts, produces sex-, age-, and BMI-conditioned biventricular anatomies whose variability matches the real cohort more closely than cVAE baselines.
SRFlow: Learning the Super-Resolution Space with Normalizing Flow
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abstract
Super-resolution is an ill-posed problem, since it allows for multiple predictions for a given low-resolution image. This fundamental fact is largely ignored by state-of-the-art deep learning based approaches. These methods instead train a deterministic mapping using combinations of reconstruction and adversarial losses. In this work, we therefore propose SRFlow: a normalizing flow based super-resolution method capable of learning the conditional distribution of the output given the low-resolution input. Our model is trained in a principled manner using a single loss, namely the negative log-likelihood. SRFlow therefore directly accounts for the ill-posed nature of the problem, and learns to predict diverse photo-realistic high-resolution images. Moreover, we utilize the strong image posterior learned by SRFlow to design flexible image manipulation techniques, capable of enhancing super-resolved images by, e.g., transferring content from other images. We perform extensive experiments on faces, as well as on super-resolution in general. SRFlow outperforms state-of-the-art GAN-based approaches in terms of both PSNR and perceptual quality metrics, while allowing for diversity through the exploration of the space of super-resolved solutions.
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Flow-based conditional cardiac anatomy generation for virtual cohorts
CAN-FLOW, a two-step conditional normalizing flow generator trained on LDDMM momenta from 2,208 UK Biobank hearts, produces sex-, age-, and BMI-conditioned biventricular anatomies whose variability matches the real cohort more closely than cVAE baselines.