A preference-fine-tuned protein language model ranks single and double mutants of CAR binding domains better than the pretrained model, finding several mutants that outperform their parent.
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Harnessing Preference Optimisation in Protein LMs for Hit Maturation in Cell Therapy
A preference-fine-tuned protein language model ranks single and double mutants of CAR binding domains better than the pretrained model, finding several mutants that outperform their parent.