Stochastic models predict remodeler competition reduces nucleosome detachment times when binding affinities match histone-DNA contacts, motors yield detachment rates proportional to bond dissociation constant times motor speed, and multimeric kinetics allow histone concentrations to rescue partials.
Parmar, John F
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Stochastic nucleosome disassembly mediated by remodelers and histone fragmentation
Stochastic models predict remodeler competition reduces nucleosome detachment times when binding affinities match histone-DNA contacts, motors yield detachment rates proportional to bond dissociation constant times motor speed, and multimeric kinetics allow histone concentrations to rescue partials.