A scalable mesh immunoaffinity device decouples nano-micro-macro scales to achieve flow-rate-independent CTC capture with >75% efficiency, 96% sensitivity and 100% specificity in 79 patients and 20 controls.
Subclassification of prostate cancer circulating tumor cells by nuclear size reveals very small nuclear circulating tumor cells in patients with visceral metastases,
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Flow Rate Independent Multiscale Liquid Biopsy for Precision Oncology
A scalable mesh immunoaffinity device decouples nano-micro-macro scales to achieve flow-rate-independent CTC capture with >75% efficiency, 96% sensitivity and 100% specificity in 79 patients and 20 controls.