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ChemRxiv , year =

Ramani, Vansh, Arora, Ashish, Kuchhal, Dhairya, Ranu, Sayan, Karmakar, Tarak , title = · DOI 10.26434/chemrxiv.15000014/v2

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physics.chem-ph 1

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2026 1

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UNVERDICTED 1

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SC3: The Multi-Solvent Solubility Challenge and Benchmark

physics.chem-ph · 2026-06-03 · unverdicted · novelty 7.0

SC3 is a new multi-solvent solubility benchmark with reproducible curation, Gold/Silver/Bronze tiers, and metrics revealing current models perform 5 times worse than the recalibrated aleatoric limit of 0.106 log S.

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  • SC3: The Multi-Solvent Solubility Challenge and Benchmark physics.chem-ph · 2026-06-03 · unverdicted · none · ref 41

    SC3 is a new multi-solvent solubility benchmark with reproducible curation, Gold/Silver/Bronze tiers, and metrics revealing current models perform 5 times worse than the recalibrated aleatoric limit of 0.106 log S.