A stochastic subsampling protocol scales topological data analysis to brain-scale matrices, but its geometric findings are generated by fitting then testing on the same data.
Mead, Journal of the Royal Statistical Society: Series D (The Statistician) 41, 27 (1992)
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ALBATROSS: Cheap Filtration Based Geometry via Stochastic Sub-Sampling
A stochastic subsampling protocol scales topological data analysis to brain-scale matrices, but its geometric findings are generated by fitting then testing on the same data.