A two-type ecDNA model shows switching does not alter total copy number distribution under equal fitness, but allows mixed cells to persist.
Extrachromosomal DNA- relieving heredity constraints, accelerating tumour evolution.Annals of Oncol- ogy, 31:884–893, 2020
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Population dynamics of multiple ecDNA types
A two-type ecDNA model shows switching does not alter total copy number distribution under equal fitness, but allows mixed cells to persist.