A new QC-based simultaneous test (QC-ST) and a covariance correction method (CoCo) are proposed to evaluate and reduce batch effects in metabolomics.
A Comparative Analysis of XGBoost
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abstract
XGBoost is a scalable ensemble technique based on gradient boosting that has demonstrated to be a reliable and efficient machine learning challenge solver. This work proposes a practical analysis of how this novel technique works in terms of training speed, generalization performance and parameter setup. In addition, a comprehensive comparison between XGBoost, random forests and gradient boosting has been performed using carefully tuned models as well as using the default settings. The results of this comparison may indicate that XGBoost is not necessarily the best choice under all circumstances. Finally an extensive analysis of XGBoost parametrization tuning process is carried out.
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High-dimensional Statistics Applications to Batch Effects in Metabolomics
A new QC-based simultaneous test (QC-ST) and a covariance correction method (CoCo) are proposed to evaluate and reduce batch effects in metabolomics.