scShapeBench supplies synthetic and real annotated single-cell datasets across four shape categories, with scReebTower outperforming PAGA and Mapper on topology-aware metrics.
Scanpy: large-scale single-cell gene expression data analysis.Genome biology, 19(1):15
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A new benchmarking framework shows virtual cell models overestimate performance on standard tests, drop sharply on unseen contexts and perturbations, and produce inconsistent rankings across metrics.
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scShapeBench: Discovering geometry from high dimensional scRNAseq data
scShapeBench supplies synthetic and real annotated single-cell datasets across four shape categories, with scReebTower outperforming PAGA and Mapper on topology-aware metrics.
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Benchmarking virtual cell models for in-the-wild perturbation response
A new benchmarking framework shows virtual cell models overestimate performance on standard tests, drop sharply on unseen contexts and perturbations, and produce inconsistent rankings across metrics.