Doubly robust, semiparametrically efficient estimators that incorporate automated computational phenotypes (ACPs) into semi-supervised inference under covariate shift, with explicit efficiency gains driven by ACPs in the unlabeled data.
Inferring the Long-Term Causal Effects of Long-Term Treatments from Short-Term Experiments
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abstract
We study inference on the long-term causal effect of a continual exposure to a novel intervention, which we term a long-term treatment, based on an experiment involving only short-term observations. Key examples include the long-term health effects of regularly-taken medicine or of environmental hazards and the long-term effects on users of changes to an online platform. This stands in contrast to short-term treatments or "shocks," whose long-term effect can reasonably be mediated by short-term observations, enabling the use of surrogate methods. Long-term treatments by definition have direct effects on long-term outcomes via continual exposure, so surrogacy conditions cannot reasonably hold. We connect the problem with offline reinforcement learning, leveraging doubly-robust estimators to estimate long-term causal effects for long-term treatments and construct confidence intervals.
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Towards the Efficient Inference by Incorporating Automated Computational Phenotypes under Covariate Shift
Doubly robust, semiparametrically efficient estimators that incorporate automated computational phenotypes (ACPs) into semi-supervised inference under covariate shift, with explicit efficiency gains driven by ACPs in the unlabeled data.