A new harmonized multi-dataset resource of small molecule perturbation transcriptomics is introduced, revealing weak cross-dataset logFC agreement but improved compound embedding performance in held-out evaluations.
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements.Nature Biotechnology, 24(9):1151–1161, September 2006
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Chem-PerturBridge: a harmonized compendium of small molecule perturbation transcriptomic effects
A new harmonized multi-dataset resource of small molecule perturbation transcriptomics is introduced, revealing weak cross-dataset logFC agreement but improved compound embedding performance in held-out evaluations.