A four-state non-equilibrium promoter model reproduces the invariant switching correlation time seen in Drosophila and links it to maximized information transmission under a switching speed limit.
Exact results for noise power spectra in linear biochemical reaction networks
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abstract
We present a simple method for determining the exact noise power spectra in linear chemical reaction networks. We apply the method to networks which are representative of biochemical processes such as gene expression and signal detection. Our results clarify how noise is transmitted by signal detection motifs, and indicate how to coarse-grain networks by the elimination of fast reactions.
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Invariant non-equilibrium dynamics of transcriptional regulation optimize information flow
A four-state non-equilibrium promoter model reproduces the invariant switching correlation time seen in Drosophila and links it to maximized information transmission under a switching speed limit.