Backdoor-adjusted ATEs on 21,098 UK Biobank participants showed total femur BMC and BMD with the largest hip fracture risk reductions (-0.0047 per SD), and adding the top 11 phenotypes to clinical variables raised AUC to 0.842 versus FRAX 0.709.
Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement
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DXA-Derived Skeletal Phenotypes and Hip Fracture Risk: A Backdoor-Adjusted Causal Analysis
Backdoor-adjusted ATEs on 21,098 UK Biobank participants showed total femur BMC and BMD with the largest hip fracture risk reductions (-0.0047 per SD), and adding the top 11 phenotypes to clinical variables raised AUC to 0.842 versus FRAX 0.709.