StaB-ddG predicts binding-affinity changes from folding-energy differences, matching FoldX accuracy on a homology-split SKEMPIv2.0 benchmark while running about 1,000 times faster.
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Predicting mutational effects on protein binding from folding energy
StaB-ddG predicts binding-affinity changes from folding-energy differences, matching FoldX accuracy on a homology-split SKEMPIv2.0 benchmark while running about 1,000 times faster.