RECON replaces GRADE's simple nonzero rule with a GMM/max-ratio threshold, removing nearly all spurious regulatory edges while keeping true ones across simulated ODE networks.
Analysis of microbial compositions: a review of normalization and differential abundance analysis.NPJ biofilms and microbiomes, 6(1):60, December 2020
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Reconstruction of Enhanced Causal Omnidirectional Network (RECON)
RECON replaces GRADE's simple nonzero rule with a GMM/max-ratio threshold, removing nearly all spurious regulatory edges while keeping true ones across simulated ODE networks.