OmicsLM integrates continuous omics embeddings into LLMs for multi-sample biological reasoning, matching specialized models on profile tasks while outperforming them and general LLMs on language-guided QA over real expression data.
Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq
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Geometric stability, defined as the directional coherence of cellular responses to perturbation, provides a framework for assessing whether resulting cellular states are stable beyond conventional metrics of intervention success.