Polarized neutron reflectometry on cell-free-expressed MscL in tethered lipid bilayers shows the fitted C-terminal protrusion drops from about 46 to 38 Å after adding pexiganan, consistent with gating toward the open state.
Python code for fitting polarized neutron reflectivity data measured from the tethered bilayer in three sub-phase contrasts
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Neutron Reflectometry Reveals Conformational Changes in a Mechanosensitive Protein Induced by an Antimicrobial Peptide in Tethered Lipid Bilayers
Polarized neutron reflectometry on cell-free-expressed MscL in tethered lipid bilayers shows the fitted C-terminal protrusion drops from about 46 to 38 Å after adding pexiganan, consistent with gating toward the open state.