A spatial-stochastic model of the mouse blastocyst shows that a large initial deposit of FGF4 in the blastocoel, about 9,500 copies, is required to produce correct EPI-PRE patterning, with the blastocoel as source and trophectoderm as sink.
Lumen Expansion Facilitates Epiblast-Primitive Endoderm Fate Specification during Mouse Blastocyst Formation
1 Pith paper cite this work. Polarity classification is still indexing.
1
Pith paper citing it
citation-role summary
background 1
citation-polarity summary
fields
q-bio.QM 1years
2025 1verdicts
CONDITIONAL 1roles
background 1polarities
background 1representative citing papers
citing papers explorer
-
Initial Luminally Deposited FGF4 Critically Influences Blastocyst Patterning
A spatial-stochastic model of the mouse blastocyst shows that a large initial deposit of FGF4 in the blastocoel, about 9,500 copies, is required to produce correct EPI-PRE patterning, with the blastocoel as source and trophectoderm as sink.