RECON replaces GRADE's simple nonzero rule with a GMM/max-ratio threshold, removing nearly all spurious regulatory edges while keeping true ones across simulated ODE networks.
A comparative analysis of mutual information methods for pairwise relationship detection in metagenomic data.BMC Bioinformatics, 25(1):266, August 2024
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Reconstruction of Enhanced Causal Omnidirectional Network (RECON)
RECON replaces GRADE's simple nonzero rule with a GMM/max-ratio threshold, removing nearly all spurious regulatory edges while keeping true ones across simulated ODE networks.