A new harmonized multi-dataset resource of small molecule perturbation transcriptomics is introduced, revealing weak cross-dataset logFC agreement but improved compound embedding performance in held-out evaluations.
SigCom LINCS: 12 data and metadata search engine for a million gene expression signatures.Nucleic Acids Re- search, 50(W1):W697–W709, July 2022
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Chem-PerturBridge: a harmonized compendium of small molecule perturbation transcriptomic effects
A new harmonized multi-dataset resource of small molecule perturbation transcriptomics is introduced, revealing weak cross-dataset logFC agreement but improved compound embedding performance in held-out evaluations.