A hydrodynamic framework shows contractile cross-linker stresses cause mechanically driven heterochromatin phase separation into droplets that wet the nuclear boundary, while active transcription fluctuations drive long-range coherent chromatin motions and deform the droplets.
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Active Hydrodynamic Theory of Euchromatin and Heterochromatin
A hydrodynamic framework shows contractile cross-linker stresses cause mechanically driven heterochromatin phase separation into droplets that wet the nuclear boundary, while active transcription fluctuations drive long-range coherent chromatin motions and deform the droplets.