3D masked autoencoders with multimodal alignment to ESM2 outperform 2D variants on single-cell microscopy tasks, reaching ROC-AUC 0.865 on protein-protein interaction and state-of-the-art AUC_micro 0.952 on localization.
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3D Masked Autoencoders are Robust Learners of Volumetric and Multimodal Cellular Representations for Microscopy
3D masked autoencoders with multimodal alignment to ESM2 outperform 2D variants on single-cell microscopy tasks, reaching ROC-AUC 0.865 on protein-protein interaction and state-of-the-art AUC_micro 0.952 on localization.