Quaternion algebras with the same subfields

G. Prasad and A. Rapinchuk asked if two quaternion division F -algebras that have the same subfields are necessarily isomorphic. The answer is known to be "no" for some very large fields. We prove that the answer is "yes" if F is an extension of a global field K so that F /K is unirational and has zero unramified Brauer group. We also prove a similar result for Pfister forms and give an application to tractable fields.