Open problems in microscopic theory of large-amplitude collective motion

Construction of the microscopic theory of large-amplitude collective motion, capable of describing a wide variety of quantum collective phenomena in nuclei, is a long-standing and fundamental subject in the study of nuclear many-body systems. Present status of the challenge toward this goal is discussed taking the shape coexistence/mixing phenomena as typical manifestations of the large-amplitude collective motion at zero temperature. Some open problems in rapidly rotating cold nuclei are also briefly discussed in this connection.