SURE-based Automatic Parameter Selection For ESPIRiT Calibration

Purpose: Parallel imaging methods in MRI have resulted in faster acquisition times and improved noise performance. ESPIRiT is one such technique that estimates coil sensitivity maps from the auto-calibration region using an eigenvalue-based method. This method requires choosing several parameters for the the map estimation. Even though ESPIRiT is fairly robust to these parameter choices, occasionally, poor selection can result in reduced performance. The purpose of this work is to automatically select parameters in ESPIRiT for more robust and consistent performance across a variety of exams. Theory and Methods: Stein's unbiased risk estimate (SURE) is a method of calculating an unbiased estimate of the mean squared error of an estimator under certain assumptions. We show that this can be used to estimate the performance of ESPIRiT. We derive and demonstrate the use of SURE to optimize ESPIRiT parameter selection. Results: Simulations show SURE to be an accurate estimator of the mean squared error. SURE is then used to optimize ESPIRiT parameters to yield maps that are optimal in a denoising/data-consistency sense. This improves g-factor performance without causing undesirable attenuation. In-vivo experiments verify the reliability of this method. Conclusion: Simulation experiments demonstrate that SURE is an accurate estimate of expected mean squared error. Using SURE to determine ESPIRiT parameters allows for automatic parameter selections.In-vivo results are consistent with simulation and theoretical results.