The entrance dynamics of polymers into a gel
classification
❄️ cond-mat.stat-mech
cond-mat.dis-nn
keywords
dynamicselectrophoresisentrancefunctionpolymerabilityagreementallow
read the original abstract
We use computer simulations to study the (driven) dynamics of a charged polymer in a disordered medium, thus mimicking the setting used in gel electrophoresis. In agreement with experiments, we find that inside the gel the mobility of the polymer is only a weak function of its length N. In contrast to this, the mean entrance time into the gel, is a very strong function of N, <tau_e > \propto N^1.3, and does not show any sign of saturation with increasing N. We rationalize this effect by means of a simple model and propose an experimental setup that should allow to increase the separation ability of gel electrophoresis significantly.
This paper has not been read by Pith yet.
discussion (0)
Sign in with ORCID, Apple, or X to comment. Anyone can read and Pith papers without signing in.