The Triplet Genetic Code had a Doublet Predecessor
classification
🧬 q-bio.GN
cs.CEq-bio.BMquant-ph
keywords
geneticacidsaminocodedoublettripletaminoacyl-trnaanalysis
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Information theoretic analysis of genetic languages indicates that the naturally occurring 20 amino acids and the triplet genetic code arose by duplication of 10 amino acids of class-II and a doublet genetic code having codons NNY and anticodons $\overleftarrow{\rm GNN}$. Evidence for this scenario is presented based on the properties of aminoacyl-tRNA synthetases, amino acids and nucleotide bases.
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