Pith. sign in

REVIEW

Stochastic model for cell polarity

Not yet reviewed by Pith; the record is open.

This paper has not been read by Pith yet. Machine review is queued; the pith claim, tier, and objections will appear here once it completes.

SPECIMEN: schema-true, not a live event

T0 review · schema-true

One-sentence machine reading of the paper's core claim.

pith:XXXXXXXX · record.json · timestamp

arxiv 1003.1404 v6 pith:52CNDWXD submitted 2010-03-06 math.PR

Stochastic model for cell polarity

classification math.PR
keywords modelcellpolaritymoleculesparameterspopulationstochasticaltschuler
verification ladder T0 review T1 audit T2 compute T3 formal T4 reserved
0 comments
read the original abstract

Cell polarity refers to the spatial asymmetry of molecules on the cell membrane. Altschuler, Angenent, Wang and Wu have proposed a stochastic model for studying the emergence of polarity in the presence of feedback between molecules. We analyze their model further by representing it as a model of an evolving population with interacting individuals. Under a suitable scaling of parameters, we show that in the infinite population limit we get a Fleming--Viot process. Using well-known results for such processes, we establish that cell polarity is exhibited by the model and also study its dependence on the biological parameters of the model.

discussion (0)

Sign in with ORCID, Apple, or X to comment. Anyone can read and Pith papers without signing in.