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Towards a Radio-guided Surgery with β⁻ Decays: Uptake of a somatostatin analogue (DOTATOC) in Meningioma and High Grade Glioma

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arxiv 1412.7389 v1 pith:TC5OMCB7 submitted 2014-12-23 physics.med-ph physics.ins-detq-bio.TO

Towards a Radio-guided Surgery with β⁻ Decays: Uptake of a somatostatin analogue (DOTATOC) in Meningioma and High Grade Glioma

Francesco Collamati , Alessandra Pepe , Fabio Bellini , Valerio Bocci , Marta Cremonesi , Erika De Lucia , Mahila Ferrari , Paola M. Frallicciardi
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Chiara M. Grana Michela Marafini Ilaria Mattei Silvio Morganti Vincenzo Patera Luca Piersanti Luigi Recchia Andrea Russomando Alessio Sarti Adalberto Sciubba Martina Senzacqua Elena Solfaroli Camillocci Cecilia Voena Riccardo Faccini
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classification physics.med-ph physics.ins-detq-bio.TO
keywords betatechniquedotatocgliomagradehighmeningiomasurgery
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A novel radio guided surgery (RGS) technique for cerebral tumors using $\beta^{-}$ radiation is being developed. Checking the availability of a radio-tracer that can deliver a $\beta^{-}$ emitter to the tumor is a fundamental step in the deployment of such technique. This paper reports a study of the uptake of 90Y labeled (DOTATOC) in the meningioma and the high grade glioma (HGG) and a feasibility study of the RGS technique in these cases.

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