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Nonlinear stability of planar traveling waves in a chemotaxis model of tumor angiogenesis with chemical diffusion

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arxiv 1903.04372 v1 pith:GMLUV3LR submitted 2019-03-11 math.AP

classification math.AP
keywords lambdastabilitysystemtravelingwavesangiogenesischemicalchemotaxis
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abstract

We consider a simplified chemotaxis model of tumor angiogenesis, described by a Keller-Segel system on the two dimensional infinite cylindrical domain $(x, y) \in \mathbb{R} \times {\mathbf S^{\lambda}}$, where $ \mathbf S^{\lambda}$ is the circle of perimeter $\lambda>0$. The domain models a virtual channel where newly generated blood vessels toward the vascular endothelial growth factor will be located. The system is known to allow planar traveling wave solutions of an invading type. In this paper, we establish the nonlinear stability of these traveling invading waves when chemical diffusion is present if $\lambda$ is sufficiently small. The same result for the corresponding system in one-dimension was obtained by Li-Li-Wang (2014) [16]. Our result solves the problem remained open in [3] at which only linear stability of the waves was obtained under certain artificial assumption.

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  1. Boundary spike-layer solutions of the singular Keller-Segel system: existence and stability

    math.AP 2019-08 conditional novelty 7.0 of 10

    For the singular Keller-Segel system on a half-line, a unique boundary spike-layer steady state exists and is nonlinearly asymptotically stable for all m≥0, provided χ is sufficiently large when m<1.

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