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Towards Automatic Generation of Shareable Synthetic Clinical Notes Using Neural Language Models

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arxiv 1905.07002 v2 pith:2U2TB3SB submitted 2019-05-16 cs.CL

classification cs.CL
keywords clinicalnotesmodelsdatalanguageconcernsneuralprivacy
verification ladder T0 review T1 audit T2 compute T3 formal
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Large-scale clinical data is invaluable to driving many computational scientific advances today. However, understandable concerns regarding patient privacy hinder the open dissemination of such data and give rise to suboptimal siloed research. De-identification methods attempt to address these concerns but were shown to be susceptible to adversarial attacks. In this work, we focus on the vast amounts of unstructured natural language data stored in clinical notes and propose to automatically generate synthetic clinical notes that are more amenable to sharing using generative models trained on real de-identified records. To evaluate the merit of such notes, we measure both their privacy preservation properties as well as utility in training clinical NLP models. Experiments using neural language models yield notes whose utility is close to that of the real ones in some clinical NLP tasks, yet leave ample room for future improvements.

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Reviewed papers in the Pith corpus that reference this work. Sorted by Pith novelty score. Full citation record

  1. DENSE: Longitudinal Progress Note Generation with Temporal Modeling of Heterogeneous Clinical Notes Across Hospital Visits

    cs.CL 2025-07 reject novelty 5.0 of 10

    DENSE synthesizes progress notes across hospital visits using retrieval over heterogeneous clinical notes, claiming temporal continuity that even exceeds gold-standard notes.

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