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PAIR-SAFE: A Paired-Agent Approach for Runtime Auditing and Refining AI-Mediated Mental Health Support

Human-Computer Interaction · Submitted 19 Jan 2026

abstract compiled · 2026-10-26 · no language-model review

The authors' main claim Our study reveals that paired-agent auditing can provide clinically grounded, transparent oversight for AI-assisted mental health support.

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arXiv ID2601.12754 (version 2)
Pith ID7G6AJN2W, Pith's permanent record of this paper and its review
CitationDong Whi Yoo, Eshwar Chandrasekharan, Jiwon Kim, Koustuv Saha, Violeta J. Rodriguez. "PAIR-SAFE: A Paired-Agent Approach for Runtime Auditing and Refining AI-Mediated Mental Health Support." arXiv:2601.12754 (2026). https://pith.science/paper/7G6AJN2W
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Compiled by classifier-1.13.0 via TypeSafe API, question bank abstract-p1-20260923, 2026-10-26: 1 request, 6,117 input tokens.

What the abstract itself states, as probabilities: claims first 0.06 · states limitation 0.18 · human participants 0.17 · controlled comparison 0.33 · randomized assignment 0.02 · states quantitative result 0.11 · compares with prior results 0.50 · mentions code or data availability 0.03.

The abstract, sentence by sentence

arXiv listing abstract v2. Results and the main claim are underlined; .

LLMs are increasingly used for mental health support, yet they can produce responses that are overly directive, inconsistent, or clinically misaligned. Most risk mitigation approaches rely on implicit alignment through training or prompting, offering limited runtime accountability. We introduce PAIR-SAFE, a paired-agent framework that integrates a Responder agent with a Judge agent grounded in the clinically validated Motivational Interviewing Treatment Integrity (MITI-4). The Judge audits each response and issues \allow{} or \revise{} decisions to guide real-time refinement. We evaluate interactions using a support-seeker simulator derived from human-annotated data. The Judge-supervised interactions show significant improvements in key MITI dimensions, including Partnership, Seek Collaboration, and overall Relational quality. Our quantitative findings are corroborated by expert evaluation, highlighting nuances of runtime supervision. Our study reveals that paired-agent auditing can provide clinically grounded, transparent oversight for AI-assisted mental health support.

background contribution method result interpretation main claim

What the classifier reports for each sentence. The number is the probability it gave the label.
#sentencerolethe authors' own workstates the main conclusionstrength
s0 LLMs are increasingly used for mental health support, yet they can produce responses that are overly directive, inconsistent, or clinically misaligned. background 0.99 0.04 0.02 asserted 0.82
s1 Most risk mitigation approaches rely on implicit alignment through training or prompting, offering limited runtime accountability. gap 0.89 0.04 0.02 asserted 1.00
s2 We introduce PAIR-SAFE, a paired-agent framework that integrates a Responder agent with a Judge agent grounded in the clinically validated Motivational Interviewing Treatment Integrity (MITI-4). contribution 0.86 0.86 0.06 asserted 1.00
s3 The Judge audits each response and issues \allow{} or \revise{} decisions to guide real-time refinement. method 0.98 0.76 0.04 asserted 0.99
s4 We evaluate interactions using a support-seeker simulator derived from human-annotated data. method 1.00 0.95 0.02 asserted 0.99
s5 The Judge-supervised interactions show significant improvements in key MITI dimensions, including Partnership, Seek Collaboration, and overall Relational quality. result 1.00 0.96 0.20 asserted 1.00
s6 Our quantitative findings are corroborated by expert evaluation, highlighting nuances of runtime supervision. result 0.93 0.90 0.09 asserted 0.99
s7 Our study reveals that paired-agent auditing can provide clinically grounded, transparent oversight for AI-assisted mental health support. interpretation 0.99 0.94 0.92 asserted 0.58

What kind of paper the classifier reports this is: method or tool 1.00 · evidence from observation or experiment 0.75.

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Every quoted sentence on this record is the authors'. Every label is from Pith's closed vocabulary, with the probability shown beside it. Every number in the measurements table is the authors', checked by code. Record as JSON

The paper
Original abstract

LLMs are increasingly used for mental health support, yet they can produce responses that are overly directive, inconsistent, or clinically misaligned. Most risk mitigation approaches rely on implicit alignment through training or prompting, offering limited runtime accountability. We introduce PAIR-SAFE, a paired-agent framework that integrates a Responder agent with a Judge agent grounded in the clinically validated Motivational Interviewing Treatment Integrity (MITI-4). The Judge audits each response and issues \allow{} or \revise{} decisions to guide real-time refinement. We evaluate interactions using a support-seeker simulator derived from human-annotated data. The Judge-supervised interactions show significant improvements in key MITI dimensions, including Partnership, Seek Collaboration, and overall Relational quality. Our quantitative findings are corroborated by expert evaluation, highlighting nuances of runtime supervision. Our study reveals that paired-agent auditing can provide clinically grounded, transparent oversight for AI-assisted mental health support.

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References
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5 arXiv papers cite this in 6 sentences

Each citing sentence is taken from the citing paper's LaTeX source and typed by Pith's classifier. A label appears at probability 0.8 or more (0.95 for support), a contest at 0.7 or more; the quoted words are the citing authors'. How each label was checked · JSON

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