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PAIR-SAFE: A Paired-Agent Approach for Runtime Auditing and Refining AI-Mediated Mental Health Support
Human-Computer Interaction · Submitted 19 Jan 2026
abstract compiled · 2026-10-26 · no language-model review
The authors' main claim Our study reveals that paired-agent auditing can provide clinically grounded, transparent oversight for AI-assisted mental health support.
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The abstract, sentence by sentence
LLMs are increasingly used for mental health support, yet they can produce responses that are overly directive, inconsistent, or clinically misaligned. Most risk mitigation approaches rely on implicit alignment through training or prompting, offering limited runtime accountability. We introduce PAIR-SAFE, a paired-agent framework that integrates a Responder agent with a Judge agent grounded in the clinically validated Motivational Interviewing Treatment Integrity (MITI-4). The Judge audits each response and issues \allow{} or \revise{} decisions to guide real-time refinement. We evaluate interactions using a support-seeker simulator derived from human-annotated data. The Judge-supervised interactions show significant improvements in key MITI dimensions, including Partnership, Seek Collaboration, and overall Relational quality. Our quantitative findings are corroborated by expert evaluation, highlighting nuances of runtime supervision. Our study reveals that paired-agent auditing can provide clinically grounded, transparent oversight for AI-assisted mental health support.
background contribution method result interpretation main claim
| # | sentence | role | the authors' own work | states the main conclusion | strength |
|---|---|---|---|---|---|
| s0 | LLMs are increasingly used for mental health support, yet they can produce responses that are overly directive, inconsistent, or clinically misaligned. | background 0.99 | 0.04 | 0.02 | asserted 0.82 |
| s1 | Most risk mitigation approaches rely on implicit alignment through training or prompting, offering limited runtime accountability. | gap 0.89 | 0.04 | 0.02 | asserted 1.00 |
| s2 | We introduce PAIR-SAFE, a paired-agent framework that integrates a Responder agent with a Judge agent grounded in the clinically validated Motivational Interviewing Treatment Integrity (MITI-4). | contribution 0.86 | 0.86 | 0.06 | asserted 1.00 |
| s3 | The Judge audits each response and issues \allow{} or \revise{} decisions to guide real-time refinement. | method 0.98 | 0.76 | 0.04 | asserted 0.99 |
| s4 | We evaluate interactions using a support-seeker simulator derived from human-annotated data. | method 1.00 | 0.95 | 0.02 | asserted 0.99 |
| s5 | The Judge-supervised interactions show significant improvements in key MITI dimensions, including Partnership, Seek Collaboration, and overall Relational quality. | result 1.00 | 0.96 | 0.20 | asserted 1.00 |
| s6 | Our quantitative findings are corroborated by expert evaluation, highlighting nuances of runtime supervision. | result 0.93 | 0.90 | 0.09 | asserted 0.99 |
| s7 | Our study reveals that paired-agent auditing can provide clinically grounded, transparent oversight for AI-assisted mental health support. | interpretation 0.99 | 0.94 | 0.92 | asserted 0.58 |
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The paper
Original abstract
LLMs are increasingly used for mental health support, yet they can produce responses that are overly directive, inconsistent, or clinically misaligned. Most risk mitigation approaches rely on implicit alignment through training or prompting, offering limited runtime accountability. We introduce PAIR-SAFE, a paired-agent framework that integrates a Responder agent with a Judge agent grounded in the clinically validated Motivational Interviewing Treatment Integrity (MITI-4). The Judge audits each response and issues \allow{} or \revise{} decisions to guide real-time refinement. We evaluate interactions using a support-seeker simulator derived from human-annotated data. The Judge-supervised interactions show significant improvements in key MITI dimensions, including Partnership, Seek Collaboration, and overall Relational quality. Our quantitative findings are corroborated by expert evaluation, highlighting nuances of runtime supervision. Our study reveals that paired-agent auditing can provide clinically grounded, transparent oversight for AI-assisted mental health support.
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References
How the literature uses it
5 arXiv papers cite this in 6 sentences
Papers citing it · 1 sentence without a confident label
Uses its method or tool 1 paper
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Following prior work on LLM-as-judge evaluation [ref] , we evaluate generated explanations with a structured rubric prompt.
Causal Stories from Sensor Traces: Auditing Epistemic Overreach in LLM-Generated Personal Sensing Explanations · LLM-Based Automated Evaluations · 0.98
Cites it as background 4 papers
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Existing approaches have primarily relied on prompt engineering, supervised fine-tuning, and reinforcement learning-based alignment methods [ref] .
LLUMI: Improving LLM Writing Assistance for Mental Health Support with Online Community Feedback · Related Work · 0.83
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LLMs inherit biases and toxic patterns from their training data, leading to concerns about fairness, safety, and harmful content generation [ref] .
Prompt PerturbAItions: Mechanisms of LLM Response Inconsistencies · Related Work · 0.92
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Multi-agent LLM systems (MAS) are increasingly deployed in coordination-heavy domains such as scheduling, care coordination, financial workflows, and enterprise pipelines [ref] , where they communicate through compressed handoffs: one agent's summary, forwarded message, or memory entry becomes the next agent's ground truth.
Facts Without Rules: Boundary Metadata Collapse in Multi-Agent LLM Handoffs · Introduction · 0.82
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