REVIEW 2 major objections 2 minor 25 references
A fractional l1/l2 sparsity prior on z-direction gradients, paired with sequential autoencoding DIP, improves inter-slice consistency in 3D CT reconstructions.
Reviewed by Pith at T0; open to challenge. T0 means a machine referee read the full paper against a public rubric. the ladder, T0–T4 →
T0 review · grok-4.3
2026-06-30 11:58 UTC pith:V27R6VSS
load-bearing objection The fractional l1/l2 sparsity on z-gradients is the unverified piece the consistency claim rests on. the 2 major comments →
Fractional-gradient Sparsity with Autoencoding Sequential Deep Image Prior for 3D CT Reconstruction
The pith
A machine-rendered reading of the paper's core claim, the machinery that carries it, and where it could break.
Core claim
The FAST-DIP framework integrates input-adaptive sequential deep image prior modeling of slices with a fractional l1/l2-based sparsity prior on gradients along the z-direction. This prior explicitly enforces inter-slice structural consistency. The alternating minimization algorithm is proven to exhibit monotonic descent of the objective and convergence to a critical point under the KL property. Experimental results for 3D X-ray computed tomography reconstruction demonstrate improved quality and structural consistency over existing DIP-based methods.
What carries the argument
The fractional l1/l2-based sparsity prior on gradients along the slice (z) direction, which captures and enforces inter-slice dependencies inside the sequential deep image prior model.
Load-bearing premise
The fractional l1/l2 sparsity prior on z-direction gradients will enforce useful inter-slice structural consistency without creating new artifacts or requiring per-dataset tuning.
What would settle it
Run the method on a standard 3D CT phantom dataset with known ground truth and measure that inter-slice structural similarity or edge consistency metrics are no better than those from plain slice-by-slice 2D DIP.
If this is right
- The alternating minimization procedure produces monotonic descent of the objective function at each step.
- The iterates converge to a critical point of the objective under the Kurdyka-Lojasiewicz property.
- Reconstruction quality and structural consistency exceed those of prior DIP-based 3D CT methods.
- The sequential modeling keeps computational cost below that of fully 3D networks while avoiding slice inconsistencies.
Where Pith is reading between the lines
- The same fractional prior could be tested on other volumetric modalities such as cone-beam CT or limited-angle tomography to check transferability.
- Adaptive choice of the fractional order based on noise level or anatomy might further improve results without manual tuning.
- The approach may reduce the data requirements for training deep networks in other inverse problems where full 3D consistency matters.
Editorial analysis
A structured set of objections, weighed in public.
Referee Report
Summary. The paper proposes FAST-DIP for 3D CT reconstruction from incomplete or noisy measurements. It integrates input-adaptive sequential deep image prior modeling of slices with a fractional l1/l2-based sparsity prior on gradients along the z-direction to enforce inter-slice structural consistency, avoiding the cost of full 3D networks and inconsistencies of slice-by-slice 2D DIP. An alternating minimization algorithm is analyzed under the majorization-minimization (MM) framework, claiming monotonic descent and convergence to a critical point under the Kurdyka-Lojasiewicz (KL) property. Experiments on 3D X-ray CT demonstrate improved reconstruction quality and structural consistency versus existing DIP-based approaches.
Significance. If the results hold, the work could advance unsupervised 3D reconstruction in medical imaging by providing a computationally lighter alternative to full 3D networks while addressing inter-slice issues via structured regularization. The theoretical analysis under the MM framework with KL-property convergence guarantees is a clear strength, as such formal support is uncommon in DIP-based inverse-problem solvers and aids reproducibility. The fractional sparsity idea may generalize to other volumetric imaging tasks if its effectiveness is confirmed.
major comments (2)
- [Regularization term definition and §4 (Experiments)] The section introducing the regularization term: the fractional l1/l2 sparsity prior on z-direction gradients is presented as the mechanism for inter-slice consistency, yet no ablation isolating its contribution, sensitivity analysis on the fractional order, or verification that it avoids new artifacts (e.g., ringing or streaks) is supplied. Overall metrics could therefore be driven by the sequential autoencoding or alternating schedule rather than this prior, which is load-bearing for the headline experimental claim.
- [Theoretical analysis (MM framework and KL property)] The theoretical analysis section: the claim that the MM framework establishes monotonic descent and convergence under the KL property is stated in the abstract, but without the explicit majorizing surrogate, the precise objective function, or the steps verifying the KL inequality for the non-convex deep-network objective, the guarantees cannot be assessed.
minor comments (2)
- Notation for the fractional order parameter and its range should be introduced earlier and used consistently when describing the prior.
- [Abstract] The abstract would benefit from one sentence summarizing the specific datasets, number of views, and quantitative metrics (PSNR/SSIM) used in the CT experiments.
Simulated Author's Rebuttal
We thank the referee for the constructive comments and positive assessment of the work's potential impact. We address each major comment below, agreeing where revisions are warranted to strengthen the manuscript.
read point-by-point responses
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Referee: [Regularization term definition and §4 (Experiments)] The section introducing the regularization term: the fractional l1/l2 sparsity prior on z-direction gradients is presented as the mechanism for inter-slice consistency, yet no ablation isolating its contribution, sensitivity analysis on the fractional order, or verification that it avoids new artifacts (e.g., ringing or streaks) is supplied. Overall metrics could therefore be driven by the sequential autoencoding or alternating schedule rather than this prior, which is load-bearing for the headline experimental claim.
Authors: We agree that isolating the contribution of the fractional l1/l2 sparsity prior is important to support the headline claims. In the revised manuscript we will add an ablation study comparing the full FAST-DIP model against a variant that disables the fractional-gradient term (while retaining the sequential DIP and alternating schedule), a sensitivity analysis over the fractional order, and visual/quantitative checks confirming the absence of new artifacts such as ringing or streaks. These additions will clarify that the prior, rather than other components, drives the reported inter-slice consistency gains. revision: yes
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Referee: [Theoretical analysis (MM framework and KL property)] The theoretical analysis section: the claim that the MM framework establishes monotonic descent and convergence under the KL property is stated in the abstract, but without the explicit majorizing surrogate, the precise objective function, or the steps verifying the KL inequality for the non-convex deep-network objective, the guarantees cannot be assessed.
Authors: We acknowledge that the theoretical section would benefit from greater explicitness. In the revision we will supply the explicit majorizing surrogate used within the MM framework, restate the precise objective function being minimized, and provide the detailed verification steps establishing the Kurdyka-Lojasiewicz inequality for the non-convex objective that includes the deep-network parameterization. These additions will make the monotonic-descent and critical-point convergence claims fully verifiable. revision: yes
Circularity Check
No significant circularity detected in derivation or claims
full rationale
The paper introduces a new objective combining sequential DIP with a fractional l1/l2 sparsity term on z-gradients, then analyzes its alternating minimization solver via standard MM majorization and KL convergence properties. Neither the prior nor the convergence result reduces to a tautology or fitted input by construction; the experimental comparisons are presented as external validation. No load-bearing self-citations, smuggled ansatzes, or self-definitional steps appear in the provided text. The method remains self-contained against external benchmarks.
Axiom & Free-Parameter Ledger
axioms (2)
- domain assumption The objective function satisfies the Kurdyka-Lojasiewicz property
- domain assumption Majorization-minimization framework applies to the proposed objective
invented entities (1)
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Fractional l1/l2-based sparsity prior on z-direction gradients
no independent evidence
read the original abstract
3D volumetric reconstruction from incomplete or noisy measurements is a fundamental problem in medical imaging and computational tomography. Deep image prior (DIP)-based methods have recently shown strong capability for solving inverse problems without requiring large training datasets. However, directly extending DIP to 3D reconstruction by fully 3D networks can incur high computational cost, while slice-by-slice 2D DIP approaches may lead to inter-slice inconsistencies due to the lack of explicit regularization along the third direction. In this paper, we propose a novel volumetric reconstruction framework, Fractional-gradient Autoencoding Sequential Tomography DIP (FAST-DIP), which integrates input-adaptive sequential deep image prior modeling of slices with fractional sparsity regularization to capture inter-slice dependencies. Specifically, we introduce a fractional l1/l2-based sparsity prior on the gradients along the slice (z) direction to explicitly enforce inter-slice structural consistency. We further provide theoretical analysis of the proposed alternating minimization algorithm under the majorization-minimization (MM) framework, establishing monotonic descent of the objective function and convergence to a critical point under the Kurdyka-Lojasiewicz (KL) property. Experimental results for 3D X-ray computed tomography (CT) reconstruction demonstrate that the proposed method improved reconstruction quality and structural consistency compared with existing DIP-based approaches.
Figures
Reference graph
Works this paper leans on
-
[1]
Tao Wang, Wenjun Xia, Jingfeng Lu, and Yi Zhang. A review of deep learning CT recon- struction from incomplete projection data.IEEE Transactions on Radiation and Plasma Medical Sciences, 8(2):138–152, 2023. 1
work page 2023
-
[2]
Chao Wang, Min Tao, James G Nagy, and Yifei Lou. Limited-angle CT reconstruction via the l_1/l_2 minimization.SIAM Journal on Imaging Sciences, 14(2):749–777, 2021. 1, 2, 3
work page 2021
-
[3]
Structure-aware sparse-view x-ray 3D reconstruction
Yuanhao Cai, Jiahao Wang, Alan Yuille, Zongwei Zhou, and Angtian Wang. Structure-aware sparse-view x-ray 3D reconstruction. InProceedings of the IEEE/CVF conference on computer vision and pattern recognition, pages 11174–11183, 2024. 1
work page 2024
-
[4]
Dmitry Ulyanov, Andrea Vedaldi, and Victor Lempitsky. Deep image prior. InProceedings of the IEEE conference on computer vision and pattern recognition, pages 9446–9454, 2018. 1, 3 11
work page 2018
-
[5]
Kuang Gong, Ciprian Catana, Jinyi Qi, and Quanzheng Li. PET image reconstruction using deep image prior.IEEE transactions on medical imaging, 38(7):1655–1665, 2018. 1
work page 2018
-
[6]
Fumio Hashimoto, Yuya Onishi, Kibo Ote, Hideaki Tashima, and Taiga Yamaya. Fully 3D implementation of the end-to-end deep image prior-based PET image reconstruction using block iterative algorithm.Physics in Medicine & Biology, 68(15):155009, 2023. 1
work page 2023
-
[7]
Feng Han, Tingkui Mu, Haoyang Li, and Abudusalamu Tuniyazi. Deep image prior plus sparsity prior: toward single-shot full-stokes spectropolarimetric imaging with a multiple- order retarder.Advanced Photonics Nexus, 2(3):036009–036009, 2023. 2
work page 2023
-
[8]
Chong Chen, Marc Vornehm, Zhenyu Bu, Preethi Chandrasekaran, Muhammad A Sultan, Syed M Arshad, Yingmin Liu, Yuchi Han, and Rizwan Ahmad. A multi-dynamic low-rank deep image prior (ML-DIP) for 3D real-time cardiovascular MRI.Journal of Cardiovascular Magnetic Resonance, page 102015, 2025. 2
work page 2025
-
[9]
Zhihao Xue, Sicheng Zhu, Fan Yang, Juan Gao, Hao Peng, Chao Zou, Hang Jin, and Chenxi Hu. A hybrid deep image prior and compressed sensing reconstruction method for highly accelerated3Dcoronarymagneticresonanceangiography.FrontiersinCardiovascularMedicine, 11:1408351, 2024. 2
work page 2024
-
[10]
Fully convolutional slice-to-volume reconstruction for single-stack MRI
Sean I Young, Yaël Balbastre, Bruce Fischl, Polina Golland, and Juan Eugenio Iglesias. Fully convolutional slice-to-volume reconstruction for single-stack MRI. InProceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition, pages 11535–11545, 2024. 2
work page 2024
-
[11]
Ismail Alkhouri, Shijun Liang, Evan Bell, Qing Qu, Rongrong Wang, and Saiprasad Ravis- hankar. Imagereconstructionviaautoencodingsequentialdeepimageprior.AdvancesinNeu- ral Information Processing Systems, 37:18988–19012, 2024. 2, 3, 6, 7, 8
work page 2024
-
[12]
Solving 3D inverse problems using pre-trained 2D diffusion models
HyungjinChung,DohoonRyu,MichaelTMcCann,MarcLKlasky,andJongChulYe. Solving 3D inverse problems using pre-trained 2D diffusion models. InProceedings of the IEEE/CVF conference on computer vision and pattern recognition, pages 22542–22551, 2023. 2
work page 2023
-
[13]
Huan Pan, You-Wei Wen, and Tieyong Zeng. Constrained total variation based three- dimension single particle reconstruction in cryogenic electron microscopy.Journal of Scientific Computing, 85(2):37, 2020. 2
work page 2020
-
[14]
Chaoyan Huang, Tingting Wu, Juncheng Li, Bin Dong, and Tieyong Zeng. Single-particle reconstruction in cryo-EM based on three-dimensional weighted nuclear norm minimization. Pattern Recognition, 143:109736, 2023. 2
work page 2023
-
[15]
Shijun Liang, Evan Bell, Qing Qu, Rongrong Wang, and Saiprasad Ravishankar. Analysis of deep image prior and exploiting self-guidance for image reconstruction.IEEE Transactions on Computational Imaging, 2025. 3
work page 2025
-
[16]
A bayesian perspec- tive on the deep image prior
Zezhou Cheng, Matheus Gadelha, Subhransu Maji, and Daniel Sheldon. A bayesian perspec- tive on the deep image prior. InProceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR), pages 5443–5451, June 2019. doi: 10.1109/CVPR.2019.00559. 3
-
[17]
URLhttps: //openreview.net/forum?id=231ZzrLC8X
HengkangWang,TaihuiLi,ZhongZhuang,TiancongChen,HengyueLiang,andJuSun.Early stopping for deep image prior.Transactions on Machine Learning Research, 2023. URLhttps: //openreview.net/forum?id=231ZzrLC8X. 3
work page 2023
-
[18]
Ludwig Ritschl, Frank Bergner, Christof Fleischmann, and Marc Kachelrieß. Improved total variation-basedCTimagereconstructionappliedtoclinicaldata.PhysicsinMedicine&Biology, 56(6):1545–1561, 2011. 3
work page 2011
-
[19]
Chaoyan Huang, Zhongming Wu, and Tieyong Zeng. Edge-guided low-light image enhancement with inertial bregman alternating linearized minimization.arXiv preprint arXiv:2403.01142, 2024. 12
-
[20]
TingtingWu,ChaoyanHuang,ShilongJia,WeiLi,RaymondChan,TieyongZeng,andSKevin Zhou. Medical image reconstruction with multi-level deep learning denoiser and tight frame regularization.Applied Mathematics and Computation, 477:128795, 2024. 3
work page 2024
-
[21]
Minimizing l1 over l2 norms on the gradient.Inverse problems, 38(6):065011, 2022
Chao Wang, Min Tao, Chen-Nee Chuah, James Nagy, and Yifei Lou. Minimizing l1 over l2 norms on the gradient.Inverse problems, 38(6):065011, 2022. 3, 6, 7
work page 2022
-
[22]
FanJiangandZhongmingWu. AninexactsymmetricADMMalgorithmwithindefiniteprox- imal term for sparse signal recovery and image restoration problems.Journal of Computational and Applied Mathematics, 417:114628, 2023. 3
work page 2023
-
[23]
Tingting Wu, Jinbo Shao, Xiaoyu Gu, Michael K Ng, and Tieyong Zeng. Two-stage image segmentationbasedonnonconvexl2-lpapproximationandthresholding.AppliedMathematics and Computation, 403:126168, 2021. 3
work page 2021
-
[24]
KarthikMohanandMaryamFazel. Iterativereweightedalgorithmsformatrixrankminimiza- tion.The Journal of Machine Learning Research, 13(1):3441–3473, 2012. 6
work page 2012
-
[25]
XENA. XENA: X-ray Extreme-range Non-imaging Analysis.https://www.darpa.mil/ research/programs/xena-x-ray-extreme. 6, 7, 8, 9, 10 13 Appendix A. Appendix: Theoretical Proofs In this section, we provide detailed proofs for the theoretical claims in the main manuscript. A.1. Proof of Lemma 1 (Majorization of the Smoothed Numerator) Proof.We consider the smoo...
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