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arxiv: 0904.1627 · v1 · pith:76NSPQVQnew · submitted 2009-04-10 · 🧬 q-bio.CB · cond-mat.stat-mech· q-bio.QM

Ratio control in a cascade model of cell differentiation

classification 🧬 q-bio.CB cond-mat.stat-mechq-bio.QM
keywords celldifferentiationmodelratiocascadecontrolledequationsparameter
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We propose a kind of reaction-diffusion equations for cell differentiation, which exhibits the Turing instability. If the diffusivity of some variables is set to be infinity, we get coupled competitive reaction-diffusion equations with a global feedback term. The size ratio of each cell type is controlled by a system parameter in the model. Finally, we extend the model to a cascade model of cell differentiation. A hierarchical spatial structure appears as a result of the cell differentiation. The size ratio of each cell type is also controlled by the system parameter.

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