Hadron Production via e+e- Collisions with Initial State Radiation

A novel method of studying e+e- annihilation into hadrons using initial state radiation at e+e- colliders is described. After brief history of the method, its theoretical foundations are considered. Numerous experiments in which exclusive cross sections of e+e- annihilation into hadrons below the center-of-mass energy of 5 GeV have been measured are presented. Some applications of the results obtained to fundamental tests of the Standard Model are listed.